In 1987, American molecular biologists Jack Strominger and Don Wiley shocked the scientific world with a supreme example of the adage "A picture is worth a thousand words."

For immunologists, their three-dimensional image of a protein published in the science magazine Nature may have been as exciting as the the discovery of the double helix structure of DNA.

Introducing their findings, Nature wrote, "The general reader will understand why every immunologist's pulse will race as he or she sees the three-dimensional structure . . . in this issue."