As the Lopez family of Truckee, California, gathered to prepare dinner on a recent evening, one subject dominated the conversation: the coronavirus vaccine that will soon be shipped out across the country, giving Americans the first concrete hope that the pandemic will eventually end.

Enrique Lopez, 46, who runs a snow-removal business, explained how he was trying to persuade his skeptical employees that the vaccine is safe. His wife, Brienne, 41, a middle school teacher, said she was desperate for the vaccine after a September bout with COVID-19 sickened her for weeks. Their two daughters just wanted to know if the vaccine would enable them to return to their pre-pandemic lives.

"I know a lot of people are scared. They don’t know what the side effects are going to be,” said Enrique Lopez, who has seen half his workforce stricken with the virus. "It’s a risk we have to take. It’s going to make us safer and go back to normal.”