The newest COVID-19 vaccine candidate to start human testing is the first where volunteers won’t get a painful injection. Instead, they’ll receive a spray through the nose.

China on Wednesday approved phase one human testing for the nasal spray vaccine, which is co-developed by researchers at Xiamen University and Hong Kong University, as well as by vaccine maker Beijing Wantai Biological Pharmacy Enterprise Co.

Intranasal spray has previously been developed as a vaccine for the flu and is recommended for use among children and adults who want to avoid the more common needle injection. While it is not the most frequent choice for delivery, scientists around the world are working to develop sprays as an alternative to muscle jabs for all sorts of vaccines.