The death toll from a new coronavirus in mainland China jumped by 73 to 563 on Thursday, its third consecutive record daily rise, as experts intensified efforts to find a vaccine for a disease that has shut down Chinese cities and forced thousands more into quarantine around the world.

Hubei province, the epicenter of the epidemic, reported 70 new deaths on Wednesday and 2,987 new confirmed cases — more than 80 percent of the total reported by Chinese authorities. The other fatalities were in Tianjin city, the northeastern province of Heilongjiang and Guizhou province in the southwest.

Hubei province in central China has been in virtual lockdown for nearly two weeks, with its train stations and airports shut and its roads sealed off. The flu-like virus was first identified in Hubei's provincial capital of Wuhan and is believed to have originated at a seafood market in the city.