Former No. 1 overall draft picks and college teammates Kyler Murray and Baker Mayfield will square off for the second time in three years when the undefeated Arizona Cardinals visit Cleveland to take on the Browns on Sunday.

Murray, the 2018 Heisman Trophy winner and the No. 1 pick in the 2019 draft, is a leading MVP candidate. The Cardinals are off to a 5-0 start for the first time since 1974.

Mayfield, the 2017 Heisman winner and top pick in 2018, has helped position the Browns (3-2) as a division contender in the AFC North.