Since the last Super Bowl 12 months ago, a pandemic has killed at least 2 million people around the world, including about 450,000 Americans. January was the deadliest month, and last week roughly one American died every 30 seconds from COVID-19.

The toll will grow through the Super Bowl on Sunday — during the big plays, among the slow-motion replays, amid the commercials, while the U.S. national anthem is sung and the halftime show is performed.

That alone makes Super Bowl LV different from the 54 that have come before it. And it presents a unique challenge for the National Football League and its broadcast partner this year, CBS Sports.