National / Science & Health Jun 3, 2020
Japan researchers create tiny bronchi to develop drug for COVID-19
It is hoped the miniature organ will serve as a better model for evaluating anti-viral drugs' efficacy than a single cell.
World / Science & Health Feb 7, 2020
CRISPR passes test: Patients show no side effects after immune systems genetically edited
U.S. scientists have succeeded in genetically editing the immune systems of three cancer patients using CRISPR without creating any side effects, a first for the tool, which is revolutionizing biomedical research. The highly anticipated results from the first phase of a clinical trial were published ...
National / Science & Health Jan 28, 2020
Osaka University transplants iPS cell-based heart cells in world's first clinical trial
An Osaka University team said it has carried out the world's first transplant of cardiac muscle cells created from iPS cells in a physician-initiated clinical trial. In the clinical project to verify the safety and efficacy of the therapy using induced pluripotent stem cells, Yoshiki ...
National / Science & Health Jan 25, 2020
An expert panel of the health ministry on Friday approved a clinical research program proposed by a Kyoto University team to transplant cartilage made from induced pluripotent stem (iPS) cells to damaged knee joints. Professor Noriyuki Tsumaki and other members of the team are planning ...
National / Science & Health Jan 13, 2020
Cancer-related genetic abnormalities have reportedly occurred during the process of transforming induced pluripotent stem (iPS) cells supplied by Kyoto University into intended cell types at recipient research institutes. None of the affected iPS cells, which are used for regenerative medicine, have been used for transplantation, ...
National / Science & Health Dec 24, 2019
Japan approves research program to grow human organs in pigs
A science ministry committee on Monday approved a research program to grow human organs, such as the pancreas, inside the bodies of pigs for use in medical transplantation. The study will be carried out by a team including Hiroshi Nagashima, professor at Meiji University, and ...
National / Science & Health Nov 30, 2019
Osaka University develops stem cell spray to treat heart failure
Osaka University said Friday it has developed a new treatment for heart failure that involves spraying stem cells directly onto the critical organ. Created by a team led by Yoshiki Sawa, a professor of cardiovascular surgery at the university, the simple treatment does not require ...
National / Science & Health Oct 24, 2019
University team to seek approval for iPS-based heart treatment trial
A university research team will seek government approval by the end of October to carry out a clinical trial using iPS cells to treat a serious heart condition, Osaka University officials said Wednesday. The treatment involves transplanting "sheets" of heart muscle cells, generated from induced ...
National / Science & Health Sep 26, 2019
Japanese-led team creates functioning structure of mini-organs from human iPS cells
A team led by Japanese researchers said Thursday that it had created a miniature multiorgan structure from human induced pluripotent stem (iPS) cells, in a world first. The one-centimeter structure consists of miniature versions of the liver, pancreas and bile duct, according to its report ...
National / Science & Health Aug 29, 2019
Osaka University team conducts world's first iPS transplant for corneal disease
The team transplanted extremely thin sheet-like corneal tissues produced from another individual’s induced pluripotent stem cells that had been stored at Kyoto University.
National Jul 24, 2019
Japanese research into growth of human organs in animals gets preliminary approval
A science ministry committee of experts on Wednesday approved Japan's first research involving the injection of human induced pluripotent stem (iPS) cells into fertilized animal eggs with the aim of growing human organs. The project led by Hiromitsu Nakauchi, a professor at the University of ...
National / Science & Health Apr 24, 2019
Eye-opener: Japanese doctor's work with iPS cells puts macular degeneration on notice
by J.J. O'Donoghue
Science has Dr. Masayo Takahashi's mother to thank, in a way, for some of the most notable developments in regenerative medicine using stem cells. More than 35 years ago when Takahashi was contemplating which career she would pursue once she graduated from high school in ...