Agribusiness is increasingly turning to natural and sustainable alternatives to chemicals as consumers rebuff genetically modified foods and concerns grow over Big Ag's role in climate change.

At the heart of the trend are innovations that harness beneficial microorganizms in the soil, including seed-coatings of naturally occurring bacteria and fungi that can do the same work as traditional chemicals, from warding off pests to helping plants flourish, according to a global patent study by research firm GreyB Services.

Much of the research in crop biotech is centered in the United States, China, Germany, Japan and South Korea, according to the U.N. agency WIPO.