KYOTO – A Japanese research team has found a more efficient way to differentiate human induced pluripotent stem cells into mature myocytes, or muscle cells, it said in a paper posted on the U.S. Plos One online science journal Wednesday.
The team has demonstrated that inducible expression of the myogenic differentiation 1 gene in immature iPS cells for at least five days drives cells along the myogenic lineage, with efficiencies reaching 70 to 90 percent, against around 40 percent in the past.
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