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OSAKA — About 10 percent of Japanese carry one of four gene mutations linked to abnormalities in blood clotting that may be connected to circulatory breakdowns such as cerebral infarction, according to the latest findings of a Japanese research group.

Patients suffering from thrombotic thrombocytopenic purpura, as well as their relatives, were found with a mutation in one of these genes, which are responsible for creating an enzyme that clots blood, according to the researchers.

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