Twitter is facing an exodus of executives and skittish advertisers as Elon Musk and his advisers take control of the social media company, prepare to lay off employees and make changes to the product.

At least five top Twitter executives — including the chief marketing officer, the chief customer officer, the head of people and diversity, and the head of product — have departed the company in recent days, according to seven people with knowledge of the matter and public statements. Two announced their departures on Twitter on Tuesday; they did not say why they had quit. More executives may leave, the people said.

At the same time, advertisers — which provide about 90% of Twitter’s revenue — are increasingly grappling with Musk’s ownership of the platform. The billionaire, who is meeting advertising executives in New York this week, has spooked some advertisers because he has said he would loosen Twitter’s content rules, which could lead to a surge in misinformation and other toxic content.