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A third COVID-19 vaccination shot appeared to significantly curb a delta-led surge in cases and prevent severe illness, according to a study in Israel, the first country to offer boosters to seniors.

Twelve days or more after a booster dose of the vaccine made by Pfizer Inc. and its partner BioNTech SE, the risk of a confirmed infection decreased more than elevenfold relative to people given only two shots, researchers from Israel’s Ministry of Health and key scientific institutes found. A third dose was associated with at least a tenfold reduction in the risk of falling seriously ill, according to the research released Friday.

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