World / Science & Health

Severe COVID-19 can damage the brain, preliminary study finds

Reuters

A preliminary study of patients hospitalized with COVID-19 has found the disease can damage the brain, causing complications such as stroke, inflammation, psychosis and dementia-like symptoms in some severe cases.

The findings are the first detailed look at a range of neurological complications of COVID-19, the researchers said, and underline a need for larger studies to find the mechanisms behind them and assist the search for treatments.

“This (is) an important snapshot of the brain-related complications of COVID-19 in hospitalized patients. It is critically important that we continue to collect this information to really understand this virus fully,” said Sarah Pett, a University College London professor who co-led the work.

The study, published in the Lancet Psychiatry journal on Thursday, looked in detail at 125 cases from across the U.K. Co-lead researcher Benedict Michael, from Liverpool University, said it was important to note that it focused on severe cases.

Data was collected between April 2 and April 26 — when the disease was spreading exponentially in the U.K.

The most common brain complication seen was stroke, which was reported in 77 of 125 patients. Of these, most were in patients over 60, and most were caused by a blood clot in the brain, known as an ischaemic stroke.

The study also found that 39 of the 125 patients showed signs of confusion or changes in behavior reflecting an altered mental state. Of these, nine had unspecified brain dysfunction, known as encephalopathy, and seven had inflammation of the brain, or encephalitis.

Michael said the findings were an important early step towards defining COVID-19’s effect on the brain. “We now need detailed studies to understand the possible biological mechanisms … so we can explore potential treatments,” he said.

Your news needs your support

Since the early stages of the COVID-19 crisis, The Japan Times has been providing free access to crucial news on the impact of the novel coronavirus as well as practical information about how to cope with the pandemic. Please consider subscribing today so we can continue offering you up-to-date, in-depth news about Japan.

Coronavirus banner