Hundreds of rebels left the last major besieged opposition enclave in Syria on Monday, with thousands more expected to follow, responding to months of pressure by a Russian-backed government offensive, the army, rebels and residents said.

A first convoy of buses with hundreds of rebels and their families, accompanied by Russian military police, departed from the city of Rastan, starting a weeklong evacuation from towns and villages in an enclave between the cities of Homs and Hama.

Rebels representing several major Free Syrian Army (FSA) factions capitulated to a Russian-imposed deal after marathon talks with Russian generals on May 2 in Dar al Kabira town in the northern Homs countryside.