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California Gov. Jerry Brown on Friday signed into law the state’s first comprehensive regulations on medical marijuana, two decades after legalization fueled disparate local rules, a gray market in cultivation and concerns about the ease of obtaining the drug.

The package of three laws, viewed by some as a possible framework for the eventual legalization of recreational marijuana in the most populous state, would establish a Bureau of Medical Marijuana Regulation and regulate such activities as cultivation and dispensary licensing.

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