Japan's first suspected case of mad cow disease shook stock markets Tuesday, prompting investors to dump shares of beef-dish restaurant chains, meat processors and milk makers while snapping up seafood firms.

The Agriculture, Forestry and Fisheries Ministry said Monday that a dairy cow in Chiba Prefecture is suspected of having contracted mad cow disease, or bovine spongiform encephalopathy.

Among firms doing business involving cows, beef-related issues saw their stock prices hardest hit Tuesday.