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Advisers to the U.S. Food and Drug Administration are expected to discuss two key questions when they meet on Sept. 17 to consider a COVID-19 vaccine booster campaign this fall: Is protection from the initial shots waning, and will boosters help?

The debate will likely be heated following the Joe Biden administration’s announcement last month — before the experts could weigh in — that the U.S. plans to start booster doses Sept. 20 if regulators approve them.

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