Thousands of Yemenis took to the streets on Saturday in the biggest demonstrations yet against the Houthi group that dominates the country, two days after President Abed Rabbo Mansour Hadi's resignation left the country in political limbo.

Houthi gunmen shot and wounded four people at a protest in the Red Sea port of Hodeida, residents said. In Sanaa, two intelligence agents were shot dead by gunmen on a motorbike, security sources said.

Witnesses said a crowd estimated at up to 10,000 people marched from Sanaa University toward Hadi's home some 3 km away and back, repeating chants denouncing both the Shiite Muslim Houthi group and predominantly Sunni al-Qaida.