Novak Djokovic and Carlos Alcaraz are on a U.S. Open collision course while American teenager Coco Gauff is chasing a breakthrough first major title as the final Grand Slam tournament of the season gets underway Monday.

A little more than six weeks after world No. 1 Alcaraz defeated Djokovic in an enthralling Wimbledon final, the two men could meet again at Flushing Meadows if the seedings go to play over the next two weeks.

Djokovic and Alcaraz whetted the tennis world's appetite for another blockbuster showdown at the Cincinnati Open last week, with 23-time Grand Slam singles winner Djokovic downing the 20-year-old Spaniard in a four-hour classic.