Novak Djokovic will be free to play in this year's U.S. Open after the government confirmed it is lifting its COVID-19 vaccine mandate on international travelers.

Djokovic, one of the highest profile athletes to remain unvaccinated, has not been able to play in the United States since the vaccine mandate came into effect in November 2021.

The 35-year-old world No. 1 last played the U.S. Open in 2021, when his bid to complete a calendar year Grand Slam ended in defeat to Russia's Daniil Medvedev in the final.

Since then, Djokovic has been a glaring absentee from U.S. tennis tournaments due to the travel mandate.

The 22-time Grand Slam singles winner applied unsuccessfully for a special exemption to enter the United States to play this year's Masters events at Indian Wells and Miami.

U.S. Open organizers, as well as the U.S. Tennis Association, both called for Djokovic to be granted an exemption.

U.S. tennis great John McEnroe was one of several who questioned the decision to continue to bar Djokovic from the United States, noting that the Serb played the U.S. Open in 2021 when the pandemic was still raging.

"He played (the U.S. Open) in 2021 and then wasn't allowed to play in 2022, someone explain that to me," McEnroe said earlier this year. "And now he's still not permitted to play? It's absurd."

Djokovic was also infamously deported from Australia last year due to his vaccine status, missing the Australian Open. He returned to Melbourne this year and won the event.

On Monday, the White House confirmed that its vaccination requirement for travelers entering the United States would be lifted on May 11.