As the pandemic enters its third year, questions about COVID-19’s origins appear increasingly distant. But if we are to forestall another coronavirus pandemic in the 21st century, understanding the causes of the current one is imperative.

Already, COVID-19 has caused more than 5.4 million deaths. But that is just the beginning: The toll of the pandemic includes increased rates of obesity, unemployment, poverty, depression, alcoholism, homicide, domestic violence, divorce and suicide. And, as the omicron variant fuels record infection rates and disrupts economies in many parts of the world, pandemic fatigue is morphing into pandemic burnout.

Our chances of eliminating COVID-19 now appear increasingly remote. But, as we attempt to figure out how to live with the virus, we must also identify the missteps — accidental and otherwise — that led us here. And that means, first and foremost, turning a critical eye toward China.