Firefighters battling a vast wildfire on Tenerife are facing another very difficult night after severe weather conditions worsened the blaze, forcing thousands to flee their homes on the Spanish holiday island, regional officials said.

The huge blaze broke out late Tuesday in a mountainous northeastern area of the island, quickly morphing into the Canary Islands' biggest-ever fire.

"It is a devastating fire ... a fire on a completely different scale, a scale that the Canary Islands has never experienced before," said Rosa Davila, head of the government of Tenerife.