For much of the pandemic, a group of places in the Asia-Pacific brought infections to zero, becoming virus-free havens in a world ravaged by the pathogen. Now, with the rise of the delta variant and the proliferation of vaccines, only one is still holding fast to that goal of eliminating COVID-19: China.

With New Zealand preparing to shift away from the zero-tolerance strategy, China’s isolation is complete, raising the stakes on how long it can stick to a playbook that requires closed borders, abrupt lockdowns and repeated disruption of social and economic activity.

One by one, "COVID-zero" places like Singapore and Australia have decided that the approach is unsustainable, pivoting instead to vaccination to protect people from serious illness and death while easing off on attempts to control the number of infections.