Britain's pharmaceutical and aerospace industries, both big exporters, are stepping up pressure on the government for assurances about their future after last week's post-Brexit deal with carmaker Nissan.

The two sectors, which have been talking to ministers since the summer, are pressing their case after written assurances by business secretary Greg Clark persuaded Nissan to invest in the country's biggest car plant, industry officials said.

Pharma and aerospace companies share the motor industry's worries about trade barriers once Britain leaves the European Union, but they also have deep concerns about regulation, their ability to recruit foreign staff and loss of EU science funding.