Waseda University decided to call off all its classes for nine days until May 29 to contain a measles outbreak among its students, university officials said.
About 55,000 students at most of its campuses, including its graduate schools, will be affected by the decision, the most at a single university since the outbreak began.
The prestigious private university based in Tokyo canceled classes starting Monday afternoon at eight campuses, including Nishiwaseda, the main campus in Shinjuku Ward, and Tokorozawa, its branch school in Saitama Prefecture.
The decision affected all 16 departments, most of the graduate school units and institutes, and about 55,000 of Waseda's more than 57,000 students. Students will be banned from entering the campuses.
However, the Kitakyushu campus, where its graduate research center is situated, and two high schools in Nerima Ward, Tokyo, and Honjo, Saitama Prefecture, will continue conducting classes.
Waseda has received 30 reports of measles infection in students since late April.
The number of measle patients in their teens and 20s has been rising sharply, particularly in the Kanto region, since mid-March. Other universities, including Sophia University and Nihon University in Tokyo, also have called off classes to contain the infectious disease.