Eddie Van Halen, whose razzle-dazzle guitar-playing — combining complex harmonics, innovative fingerings and ingenious devices he patented for his instrument — made him the most influential guitarist of his generation and his band, Van Halen, one of the most popular rock acts of all time, died on Tuesday. He was 65.

Van Halen’s son, Wolfgang, said in a statement that his father had "lost his long and arduous battle with cancer.” The statement did not say where he died.

Van Halen structured his solos the way Macy’s choreographs its Independence Day fireworks shows: shooting off rockets of sound that seemed to explode in a shower of light and color. His outpouring of riffs, runs and solos was hyperactive and athletic, joyous and wry, making deeper or darker emotions feel irrelevant.