A high-profile 2013 study that concluded that different kinds of happiness are associated with dramatically different patterns of gene activity is fatally flawed, according to an analysis published on Monday that tore into its target with language rarely seen in science journals.

The new paper, published like the first in Proceedings of the National Academy of Sciences, slams the research for "dubious analyses" and "erroneous methodology" and says it "conjured nonexistent effects out of thin air."

In the 2013 study, researchers had adults answer a 14-item questionnaire meant to sort them into two groups: interested in hedonic well-being (fun and selfish pleasure) or eudaimonic well-being (leading a meaningful life).