Young, casual marijuana smokers experience potentially harmful changes to their brains, with the drug altering regions of the mind related to motivation and emotion, researchers have found.

The study, published Wednesday in the Journal of Neuroscience, differs from many other pot-related research projects that are focused on chronic, heavy users of cannabis.

The collaborative effort between Northwestern University's medical school, Massachusetts General Hospital and Harvard Medical School showed a direct correlation between the number of times users smoked and abnormalities in the brain.