Permanent residency

Having been granted permanent residency a couple of years ago, I have been concerned about ensuring that I do not jeopardize it by overlooking any technicalities.

If I have a valid re-entry permit, can I simply return to Japan before the entry permit expires to obtain another and then go back to my home country? Are there grounds on which you can be denied a multiple re-entry permit?

Permanent residency is permanent. You do not have to renew it.