The framework nuclear deal with Iran could be a regional and global geopolitical game changer and constitute the defining foreign policy legacy of President Barack Obama’s presidency.

Suspicions that Iran is using its peaceful nuclear program as a cover for clandestine weapons acquisition have persisted for a long time. Nuclear weaponization by Iran would have a series of negative consequences for every component of the nuclear arms control agenda, from increasing proliferation pressures in and beyond the region to heightened risks of nuclear terrorism, use of nuclear weapons, and setbacks to efforts to cut global nuclear stockpiles and reduce their role and salience in national security doctrines.

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