MELBOURNE, Australia — Louise Brown, the first person to be conceived outside a human body, turned 30 last year. The birth of a "test-tube baby," as the headlines described in vitro fertilization, was highly controversial at the time.

Leon Kass, who subsequently served as chair of President George W. Bush's Council on Bioethics, argued that the risk of producing an abnormal infant was too great for an attempt at IVF ever to be justified. Some religious leaders also condemned the use of modern scientific technology to replace sexual intercourse, even when it could not lead to conception.

Since then, some 3 million people have been conceived by IVF, enabling otherwise infertile couples to have the child they longed for.