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The World Health Organization forecasts that those most vulnerable to COVID-19, such as older people, will need to get an annual vaccine booster to be protected against variants, an internal document shows.

The estimate is included in a report, which was to be discussed on Thursday at a board meeting of Gavi, a vaccine alliance that co-leads the WHO's COVID-19 vaccine program COVAX. The forecast is subject to changes and is also paired with two other less likely scenarios.

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