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Britain is preparing to become the first country to roll out the Pfizer-BioNTech COVID-19 vaccine this week, initially making the shot available at hospitals before distributing stocks to clinics, the government said on Sunday.

The first doses are set to be administered on Tuesday, with the National Health Service giving top priority to vaccinating the over-80s, front-line health care workers and care home staff and residents.

Britain gave emergency use approval for the vaccine developed by Pfizer and BioNTech last week — jumping ahead in the global race to begin the most crucial mass inoculation program in history.

In total, Britain has ordered 40 million doses — enough to vaccinate 20 million people in the country of 67 million.

About 800,000 doses are expected to be available within the first week.

Initial doses that have arrived from Belgium are being stored in secure locations across the country, where they will be quality checked, the health ministry said.

The Pfizer-BioNTech vaccine has onerous storage requirements. It needs to be kept at minus 70 degrees Celsius (minus 94 Fahrenheit) and only lasts five days in a regular fridge.

For that reason, the health ministry said the vaccine would first be administered in 50 hospitals. It said it would take a few hours to defrost each vaccine and prepare it for use.

NHS England has written to general practitioners, telling them to get ready to start giving vaccinations from Dec. 14.

Groups of local doctors will operate more than 1,000 vaccination centers across the country, the government said.

Boxes of the vaccine contain five packs of 975 doses, but special regulatory approval is needed to split them up. A senior medical official has said that while he was hopeful it would be possible to split the packs and deliver straight to care homes, it was not guaranteed.

Britain is among the first nations to roll out vaccinations outside the context of a clinic trial, raising hopes that the tide could soon turn against a virus that has killed nearly 1.5 million people globally and hammered the world economy.

Russia began distributing its Sputnik V COVID-19 vaccine through 70 clinics in Moscow on Saturday, although the shot has not finished its final trials.

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