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In Wuhan, the central Chinese city that’s ground zero of the deadly new virus spreading through the country, a sense of fear is rapidly taking hold.

On Thursday morning, the city’s some 11 million residents woke to learn it’s now on lockdown, with public transport halted, flights out canceled and trains not running right on the eve of the Lunar New Year holiday that traditionally unites families for days of feasting.

It’s a dramatic escalation for Wuhan, which has found itself at the epicenter of a potentially global health crisis after a market selling freshly slaughtered meat and live animals was identified as the source of an outbreak that’s killed over a dozen people and sickened hundreds.

The outbreak has residents questioning their every move.

Student Yi Zixuan is terrified a meal Sunday with friends near a hospital may have exposed her to the new coronavirus, which causes pneumonia in those infected.

“I didn’t wear a mask,” said Yi, 21. “I’ve canceled a trip to Changsha during the Lunar New Year holiday and I’m even canceling my plans to watch movies at the cinema. I’ll try to stay home as much as I can.”

With the death toll from the virus rising markedly last weekend, and more cases identified, life in Wuhan has gone from normal to fraught in a matter of days. Within hours of the travel restrictions being announced, hundreds of cars queued in barely moving traffic at a toll booth for a highway out of the city.

Home to a bustling port on the Yangtze River, Wuhan is a transport hub for central China with a number of high-speed rail lines converging there. A former British settlement, it still retains architecture from that period, with steel and car manufacturing among the main employers.

When Yi left home Monday morning, she says about 20 percent of people wore protective face masks; by evening, she estimated the number had soared to about 80 percent. Across the city, people are already finding ways to carry on — with caution. Yi’s mother is still gathering with friends to play mahjong, but now they check each other’s body temperatures before playing.

“Our fate is at the mercy of the gods,” Yi said. “It’s hard to tell who carries the virus so we have no other options.”

For Wuhan native Guo Zirui, that means an unusual separation. One of the 21-year-old student’s parents works at a local hospital so he says his family decided to send him back to his dormitory in Beijing, where he’s studying at Tsinghua University.

“The hospital is not a hotel so medical staff have to go back home after work,” he said, speaking by mobile phone from Wuhan railway station on his way back to the capital on Wednesday afternoon. “The situation is still unclear and we don’t know if it’s safe for me to keep staying in Wuhan.”

The New Year holiday — when hundreds of millions of people are set to travel in the biggest annual migration of humans on the planet — is providing a significant challenge for Chinese authorities striving to contain the outbreak that has also infected people from Thailand to the U.S. On Wednesday, China announced a stepping up of controls at transport points across the country and increased screening of travelers. But officials admitted there’s much they don’t know about the new virus, which belongs to the same family of bugs as SARS, a respiratory outbreak that killed about 800 people 17 years ago.

The coronavirus symptoms include fever, cough or chest tightness, and difficulty breathing. While footage on social media showed deserted streets and vacant subway platforms in Wuhan, retiree Wang Ping, 61, said in an interview before the lockdown that people were still venturing out to shop and visit relatives.

“I don’t wear masks, because I’m in great health condition,” Wang said. “For sure they will get it under control.”

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