Marmite may be brain food, study says


In a world bitterly divided into pro- and anti-Marmite factions, lovers of the tangy British spread have found support from an unexpected quarter: brain science.

Experiments found that volunteers who ate a daily spoonful of the dark-brown yeast extract seemed to have higher levels of a neuron chemical associated with a healthy brain. Marmite also has high levels of vitamin B-12, the investigators say.

In a study published on Wednesday, psychologists at the University of York in northern England recruited 28 volunteers and divided them into two groups. One group ate a teaspoon (5.7 cc) of Marmite each day for a month; the other ate a daily teaspoon of peanut butter.

The volunteers wore noninvasive skullcaps fitted with electrodes to monitor brain activity while they looked at a screen with a visual stimulus — a large stripey pattern that flickered at a regular rate.

Compared with the peanut butter group, the Marmite group showed a reduction of 30 percent in response to the stimulus.

The work, published in the Journal of Psychopharmacology, sheds a powerful light on how diet can affect brain activity, the researchers say.

How Marmite worked was not clinically investigated.

But the presumption is that it boosts levels of an important neurotransmitter called gamma-amino-butyric acid. GABA acts as a kind of brake on overexcited brain cells. It binds to neurons and reduces their activity, helping to provide balance in the brain.

Scientists have previously theorized that GABA helps to dampen fear or anxiety, which happens when neurons are overstimulated. The anti-anxiety drug benzodiazepine, for instance, works by beefing up GABA’s effectiveness, and abnormal levels of GABA have been associated with epilepsy.

“This study suggests that eating Marmite is potentially good for you in that it seems to increase a chemical messenger associated with healthy brain function,” lead authors Daniel Baker and Anika Smith said in an interview. “There could potentially be beneficial effects for people with some neurological disorders linked to GABA.”

The pair said they are not clinicians or dieticians, so they were unwilling to recommend a healthy limit for eating Marmite. “However, there is no evidence that normal consumption of Marmite has any negative effects,” they said.

Compared with the same quantity of peanut butter, the team found that Marmite had around 116 times more vitamin B-12, three times more vitamin B-6 and nearly twice as much glutamate as peanut butter.

The new study appears in a specialist peer-reviewed publication, the Journal of Psychopharmacology.

Deemed a quintessential British food, Marmite has been the subject of a “love it or hate it” debate that has rumbled on for years, including a tongue-in-cheek campaign on social media to abolish the condiment.

One joke put around by detractors is thus: “I was in a good mood last week. I entered a competition and won a year’s supply of Marmite — one jar!”