Confirmation that a missing Malaysian airliner crashed in the Indian Ocean opens the way for what could be one of the most costly and challenging air crash investigations in history.

Malaysian Prime Minister Najib Razak said Flight MH370 had ended far from any runway, signalling a shift of focus from a search for survivors to a mission to recover bodies and hunt for debris and black boxes.

Based on fresh analysis of satellite data by U.K.-based Inmarsat, Malaysia's decision to declare the aircraft lost in international waters marks a new phase in a search which has narrowed to an area southwest of Perth, Australia.