Guinness World Records announced in 2012 that Sir Arthur Conan Doyle's Sherlock Holmes was the most portrayed character on film and TV, depicted 254 times by more than 75 different actors.

While familiar with the original, Japanese audiences also know the detective via an anime titled "Sherlock Hound" (co-directed by Hayao Miyazaki no less) and a weekly manga called "Detective Conan," which was also made into a popular TV series.

On April 27, however, Sherlock and his partner, Dr. John Watson, will be resurrected yet again by actresses Yuko Takeuchi and Shihori Kanjiya in the Hulu/HBO Asia series "Miss Sherlock." It's a less common depiction of the pair, with both women living in present-day Tokyo (though the American TV series "Elementary" gave audiences Lucy Liu as Dr. Joan Watson in modern New York), and that results in a refreshing take on the story despite a somewhat superficial tagline of the "most beautiful Sherlock ever."