Attorney General Eric Holder was to announce Monday that low-level, nonviolent drug offenders with no ties to gangs or large-scale drug organizations will no longer be charged with offenses that impose severe mandatory sentences.

The new Justice Department policy is part of a comprehensive prison reform package that Holder was to reveal in a speech to the American Bar Association in San Francisco, according to senior department officials. He is also expected to introduce a policy to reduce sentences for elderly, nonviolent inmates and find alternatives to prison for nonviolent criminals.

Justice Department lawyers have worked for months on the proposals, which Holder wants to make the cornerstone of the rest of his tenure.